Consider Matthew 7:1. Judging people for their emotions is a waste of time.
If you have an issue with the beliefs behind the anger, you may take that to Law and Order. But right now I don’t really have a belief. All I have is a subjective interpretation of artwork and an emotion generated from that interpretation, and if 4 years of English class has taught me anything, it’s that people interpret artwork based on the context of their personal experiences. Lil’s personal experiences + that comic = anger. That’s it. She doesn’t have control over her personal experiences, so you have no right to judge her for them, the interpretation, or the emotion.
The responsibility in this case is not “I am not allowed to interpret the art this way”. That is self-hatred. The responsibility of an interpreter of artwork is to own the experiences and beliefs that lead to that interpretation, and not insult the artist or people who interpret artwork differently as a result of your interpretation. In my view Lil has fulfilled both of these responsibilities so far.